Limonoids: Advances in Extraction, Characterization, and Applications (2025)

Saber, F. R., Salehi, H., Khallaf, M. A., Rizwan, K., Gouda, M., Ahmed, S., Zengin, G., Zhang, L., Rakmai, J., Secomandi, E., Lucini, L., & Simal-Gandara, J. (2025). Limonoids: Advances in Extraction, Characterization, and Applications. Food Reviews International, 1-62. https://doi.org/10.1080/87559129.2025.2456494

Saber, Fatema R. ; Salehi, Hajar ; Khallaf, Moustafa Ali et al. / Limonoids: Advances in Extraction, Characterization, and Applications. In: Food Reviews International. 2025 ; pp. 1-62.

@article{42a4e0e3a1c44f9cbd5496db46888e37,

title = "Limonoids: Advances in Extraction, Characterization, and Applications",

abstract = "Limonoids are highly oxygenated terpenoids that occur exclusively in certain plant families. Meliaceae and Rutaceae encompass many limonoids with a myriad of biological potential. There has been a growing interest in the consumption and exploitation of functional limonoids. Several analytical techniques have been employed to characterize and detect various limonoids. This review explores advanced extraction techniques and novel applications of limonoids in health, agriculture and the food industry, including various pharmaceutical formulations and their potential uses. Additionally, it discusses the different analytical tools used for limonoids characterization, including X-ray crystallography, Fourier Transform Infrared Spectroscopy and Ultra Performance Liquid Chromatography-Mass Spectrometry, among others. Biological interactions of limonoids with the protein targets are also highlighted.",

keywords = "Limonoids, phytochemistry, formulations, extraction, food industry, spectroscopy, Limonoids, phytochemistry, formulations, extraction, food industry, spectroscopy",

author = "Saber, {Fatema R.} and Hajar Salehi and Khallaf, {Moustafa Ali} and Komal Rizwan and Mostafa Gouda and Shakeel Ahmed and Gokhan Zengin and Leilei Zhang and Jaruporn Rakmai and Elena Secomandi and Luigi Lucini and Jesus Simal-Gandara",

year = "2025",

doi = "10.1080/87559129.2025.2456494",

language = "English",

pages = "1--62",

journal = "Food Reviews International",

issn = "8755-9129",

publisher = "Taylor and Francis Ltd.",

}

Saber, FR, Salehi, H, Khallaf, MA, Rizwan, K, Gouda, M, Ahmed, S, Zengin, G, Zhang, L, Rakmai, J, Secomandi, E, Lucini, L & Simal-Gandara, J 2025, 'Limonoids: Advances in Extraction, Characterization, and Applications', Food Reviews International, pp. 1-62. https://doi.org/10.1080/87559129.2025.2456494

Limonoids: Advances in Extraction, Characterization, and Applications. / Saber, Fatema R.; Salehi, Hajar; Khallaf, Moustafa Ali et al.
In: Food Reviews International, 2025, p. 1-62.

Research output: Contribution to journal › Meeting Abstract

TY - JOUR

T1 - Limonoids: Advances in Extraction, Characterization, and Applications

AU - Saber, Fatema R.

AU - Salehi, Hajar

AU - Khallaf, Moustafa Ali

AU - Rizwan, Komal

AU - Gouda, Mostafa

AU - Ahmed, Shakeel

AU - Zengin, Gokhan

AU - Zhang, Leilei

AU - Rakmai, Jaruporn

AU - Secomandi, Elena

AU - Lucini, Luigi

AU - Simal-Gandara, Jesus

PY - 2025

Y1 - 2025

N2 - Limonoids are highly oxygenated terpenoids that occur exclusively in certain plant families. Meliaceae and Rutaceae encompass many limonoids with a myriad of biological potential. There has been a growing interest in the consumption and exploitation of functional limonoids. Several analytical techniques have been employed to characterize and detect various limonoids. This review explores advanced extraction techniques and novel applications of limonoids in health, agriculture and the food industry, including various pharmaceutical formulations and their potential uses. Additionally, it discusses the different analytical tools used for limonoids characterization, including X-ray crystallography, Fourier Transform Infrared Spectroscopy and Ultra Performance Liquid Chromatography-Mass Spectrometry, among others. Biological interactions of limonoids with the protein targets are also highlighted.

AB - Limonoids are highly oxygenated terpenoids that occur exclusively in certain plant families. Meliaceae and Rutaceae encompass many limonoids with a myriad of biological potential. There has been a growing interest in the consumption and exploitation of functional limonoids. Several analytical techniques have been employed to characterize and detect various limonoids. This review explores advanced extraction techniques and novel applications of limonoids in health, agriculture and the food industry, including various pharmaceutical formulations and their potential uses. Additionally, it discusses the different analytical tools used for limonoids characterization, including X-ray crystallography, Fourier Transform Infrared Spectroscopy and Ultra Performance Liquid Chromatography-Mass Spectrometry, among others. Biological interactions of limonoids with the protein targets are also highlighted.

KW - Limonoids

KW - phytochemistry

KW - formulations

KW - extraction

KW - food industry

KW - spectroscopy

KW - Limonoids

KW - phytochemistry

KW - formulations

KW - extraction

KW - food industry

KW - spectroscopy

UR - http://hdl.handle.net/10807/313125

U2 - 10.1080/87559129.2025.2456494

DO - 10.1080/87559129.2025.2456494

M3 - Meeting Abstract

SN - 8755-9129

SP - 1

EP - 62

JO - Food Reviews International

JF - Food Reviews International

ER -

Saber FR, Salehi H, Khallaf MA, Rizwan K, Gouda M, Ahmed S et al. Limonoids: Advances in Extraction, Characterization, and Applications. Food Reviews International. 2025;1-62. doi: 10.1080/87559129.2025.2456494